Effects of Cement Dust Exposure on Liver Function among Construction Workers in Akala Express

Introduction: Exposure to cement dust presents serious threats to one's health at work, especially for construction workers. Its possible effects on liver function are still little understood, despite the well-established benefits on respiratory and skin health.

Aim/Objective: This study investigates the effects of cement dust exposure on liver function among construction workers in Akala Express, focusing on biomarkers such as AST, ALT, ALP, Bilirubin, Albumin, and Total Protein.

Method:50 exposed and 50 non-exposed people, matched for age and demographics, participated in a case-control study. Standardized biochemical techniques were used to gather blood samples and test them for liver indicators. To do statistical analysis, SPSS version 24.0 was used. The data was summarized using descriptive statistics, and the amounts of biomarkers in each group were compared using independent t-tests. The association between exposure length and liver dysfunction was evaluated using chi-square testing.

Results: ALT levels were significantly lower in the exposed group compared to the control group (p = 0.004), while other liver biomarkers (AST, ALP, Albumin, and Total Protein) showed no significant differences between groups (p > 0.05). Liver dysfunction was observed in 8% of the exposed group but absent in controls. Chi-square analysis indicated a significant association between longer exposure duration and liver dysfunction (p = 0.026).

Conclusion: Prolonged exposure to cement dust significantly reduces ALT levels, indicating potential liver stress. However, other liver biomarkers remained within normal ranges, suggesting adaptive mechanisms may mitigate severe damage. The results highlight the importance of enforcing protective measures and conducting longitudinal studies to better understand long-term effects.